Editorial Comments 1947..1951
نویسندگان
چکیده
Treatment of patients with IgA nephropathy (IgAN) remains a matter of debate. Why, given that IgAN is the most prevalent glomerulonephritis in several countries, does it cause end-stage renal disease (ESRD) in 15–20% of patients within 10 years of the apparent onset of disease, and account for 10% of incident ESRD patients? At a first look, this results from the heterogeneity of patients referred for IgAN. In fact, there are important differences in renal biopsy policy between centres and countries, leading to very dissimilar patient populations at inclusion in treatment protocols. Most of the patients have only a far potential diagnosis lacking histological documentation, and some are seen only at late stages of renal disease, precluding accurate treatment evaluation and inclusion in controlled studies. Finally, patients have different lengths of disease course, associated with distinct evolution potentials as assessed by the severity of either clinical presentation or histological lesions.
منابع مشابه
Comments in; Afshari R. Integration of Medical Education and Health Services Meets Accountability Challenges and Excellence of Education? FMEJ 2012: 2 (1): 2 [editorial].
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متن کاملA study of the adjustment in foster homes of sixteen rejected children placed by the Worcester Children's Friend Society from January, 1947 - July, 1950
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Pernicious anemia from Addison to folic acid.
‘947. HEINLE, R. W., AND WELCH, A. D. : J. A. M. A. 133. 739, 1947. 6. HEINLE, R. W., AND \VELCH, A. D.:J. A. M. A. 133. 739, 1947. VILTER, C. F., VITLER, R. \V., AND Spias, T. D. :J. Lab. & Clin. Med. 32 162., 1947. MEYER, L. M.: BLOOD 2. 50, 1947. . A warning regarding the use of folic acid. Editorial, N. E.J. Med. .13: 713, 1947. 8. SUAREZ, R.: Editorial correspondence, N. E. J. Med. 238.34,...
متن کاملHomologous tissue sensitization; failure to produce joint and kidney lesions or precipitins with homologous tissues plus streptococci.
Atrophic arthritis has been produced experimentally in animals, but not under conditions comparable to those observed in man. Study of the disease has thus been handicapped. Homologous tissues plus adjuvants have been used successfully to produce organ-specific lesions in the kidneys (Klinge and Knepper, 1935; Schwentker and Comploier, 1939; Cavelti and Cavelti, 1945a, b, c; Sprunt and others, ...
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تاریخ انتشار 2004